| 1. | Stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate 司他夫定通过细胞激酶磷酸化,形成司他夫定的三磷酸盐而发挥抗病毒活性。 |
| 2. | The fact that stevioside is glycosylated at position c13 could explain the absence of mutagenicity . the active metabolite of steviol responsible for its mutagenic activity is not known 甜菊糖?的c13位置被糖基化,是没有引起突变的原因。目前,还没有找出引发突变能力的甜菊醇活性代谢物。 |
| 3. | An active metabolite was obtained by purification with precipitated by ethanol , sephadex g - 25 gel , deae - cellulose ion exchange resin and silica gel column chromatography 经乙醇( 95 )沉淀、 sephadexg - 25凝胶层析、 deae -纤维素离子交换层析和硅胶层析纯化,得到抑制黑曲霉生长的单一组分。 |
| 4. | The biological characterization and the absorption capacity of a myxobacterium nust03 for the heavy metal is investigated . an active metabolite is separated and purified from the fermentation by the nust03 研究盐土粘细菌nusto3菌株的形态结构、生理生化特性和吸附重金属的能力并分离纯化其胞外活性物质。 |
| 5. | The active metabolite of steviol responsible for its mutagenic activity is not known . while some data suggest that epoxidation may be involved in the metabolic activation of steviol , other data indicate that the active metabolite is not an epoxide 有些数据指出,甜菊醇在代谢活化的过程中,可能牵涉环氧化作用,但其他数据显示,甜菊醇的活性代谢物并不是环氧化物。 |
| 6. | While some data suggest that epoxidation may be involved in the metabolic activation of steviol , other data indicate that the active metabolite is not an epoxide . preliminary data indicate that steviol may be activated to a mutagenic metabloite by human liver microsomes 有些数据指出,甜菊醇在代谢活化的过程中,可能牵涉环氧化作用,但其他数据显示,甜菊醇的活性代谢物并不是环氧化物。 |
| 7. | Mmf is the morpholinoethyl ester prodrug of its active metabolite inycophenolic acid ( mpa . mpa is a noncompetitive , reversible inhibitor of the enzyme inosine 5 ' - monophosphate dehydrogenase ( impdh ) , which plays a maor role in the de novo spohesis of guansine nucleotides Balb c和c57bl 6小鼠是纯系的同种小鼠,具有不同的主要组织相容性抗原( mhc i 、 11 ) ,可进行同种排斥反应的兔疫学研究。 |